Contact Us

Antitope Ltd
Babraham Research Campus
Babraham
Cambridge CB22 3AT
United Kingdom

Telephone: +44(0) 1223 496190
Fax: +44(0) 1223 496191
Email: This e-mail address is being protected from spambots. You need JavaScript enabled to view it

PolyTherics Ltd
The London Bioscience Innovation Centre
2 Royal College Street
London NW1 0NH
United Kingdom

Telephone: +44 (0)20 7691 4927
Email: This e-mail address is being protected from spambots. You need JavaScript enabled to view it

Composite Vaccines

Antitope has established technologies for measuring CD8+ (cytotoxic) T cell epitopes and regulatory T cell epitopes (Tregs) as well as CD4+ T cell epitopes in order to generate more effective recombinant vaccines. These have been introduced into various vaccines in an optimized form to achieve a broad coverage of MHC class I and MHC class II-associated responses. For vaccination in indications such as infectious disease and cancer selection of immunodominant T cell epitopes that bind to a large number of MHC alleles is often associated with improved efficacy.