EpiScreen™ can be used to map T cell epitopes within a protein to determine its potential immunogenicity. EpiScreen™ T cell epitope mapping has been used to determine the precise location, number and magnitude of T cell epitopes in many toxins, protein scaffolds and proteins (both human and non-human) prior to deimmunisation.
For further information, please contact us.
1 Baker MP and Jones TD. Identification and removal of immunogenicity from therapeutic proteins. Current Opinion Drug Discovery Development. 2007; 10(2):219-227
*We work with a range of established providers of blood who supply samples that are used with donor consent.